Combined line-cross and half-sib QTL analysis of crosses between outbred lines
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چکیده
منابع مشابه
Combined line-cross and half-sib QTL analysis of crosses between outbred lines.
Data from an F 2 cross between breeds of livestock are typically analysed by least squares line-cross or half-sib models to detect quantitative trait loci (QTL) that differ between or segregate within breeds. These models can also be combined to increase power to detect QTL, while maintaining the computational efficiency of least squares. Tests between models allow QTL to be characterized into ...
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Estimating the line origin of chromosomal sections from marker genotypes is a vital step in quantitative trait loci analyses of outbred line crosses. The original, and most commonly used, algorithm can only handle moderate numbers of partially informative markers. The advent of high-density genotyping with SNP chips motivates a new method because the generic sets of markers on SNP chips typical...
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MAPfastR is an R package for mapping quantitative trait loci (QTL) in outbred line crosses. It contains all the functions required to perform a QTL analysis in outbred lines. Some of the functions implement different algorithms that can be used interchangeably and it is up to the user to decide which will be applied. This gives the user a certain degree of flexibility when constructing the anal...
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We provide a theoretical framework for quantitative trait locus (QTL) analysis of a crossed population where parental lines may be outbred and dominance as well as inbreeding are allowed for. It can be applied to any pedigree. A biallelic QTL is assumed, and the QTL allele frequencies can be different in each breed. The genetic covariance between any two individuals is expressed as a nonlinear ...
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In an experimental cross between Meishan and Dutch Large White and Landrace lines, 619 F(2) animals and their parents were typed for molecular markers covering the entire porcine genome. Associations were studied between these markers and two fatness traits: intramuscular fat content and backfat thickness. Association analyses were performed using interval mapping by regression under two geneti...
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ژورنال
عنوان ژورنال: Genetical Research
سال: 2005
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672305007597